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| Symbol | EFNB3 |
| Full Name | Ephrin B3 |
| Chromosome | 19p13.3 |
| NCBI Gene | 1949 |
| OMIM | 601168 |
| Ensembl | ENSG00000108947 |
| UniProt | Q99968 |
| Associated Diseases | Neurodevelopment |
EFNB3 (Ephrin B3) is a transmembrane ligand for EPHB receptors that mediates cell-cell communication and regulates synaptic plasticity. As an ephrin family member, EFNB3 plays crucial roles in neural development, synaptic function, and cellular signaling. Altered EFNB3 expression has been implicated in neurodegenerative diseases, particularly Alzheimer's disease and Parkinson's disease.
EFNB3 is an ephrin-B ligand that participates in neural circuit formation. It regulates axon guidance and synaptic development.
Expressed in developing and adult brain.