| ATP10B — ATPase Phospholipid Transporting 10B | |
|---|---|
| Symbol | ATP10B |
| Full Name | ATPase Phospholipid Transporting 10B |
| Chromosome | 12q24.31 |
| NCBI Gene | 23195 |
| Ensembl | ENSG00000137727 |
| OMIM | 620226 |
| UniProt | Q9Y5K5 |
| Diseases | Parkinson's Disease, Dementia with Lewy Bodies |
| Expression | Substantia Nigra, Brain |
| Key Mutations | |
| Loss-of-function variants | |
ATP10B (ATPase Phospholipid Transporting 10B) is a gene located on chromosome 12q24.31 that plays a critical role in neurodegenerative disease. Mutations in ATP10B are associated with Parkinson's Disease, Dementia with Lewy Bodies. The gene is catalogued as NCBI Gene ID 23195 and OMIM 620226.
The ATP10B gene encodes a protein that is expressed in multiple brain regions including Substantia Nigra, Brain. The normal function of this gene product is essential for neuronal health and survival.
Expression data is available from the Allen Human Brain Atlas.
ATP10B mutations are linked to the following neurodegenerative conditions:
Page auto-generated from NeuroWiki gene database. Last updated: 2026-02-26.