Lsm1 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
LSM1 (LSM1 Homolog, mRNA Surveillance Complex) is an RNA-binding protein belonging to the Sm-like family. LSM1 forms ring-shaped heptameric complexes that bind to RNA molecules and participate in various aspects of RNA metabolism, including mRNA decapping, splicing, and decay. [1]
| Attribute | Value | [2]
|-----------|-------| [3]
| Protein Name | LSM1 Homolog | [4]
| Gene | LSM1 | [5]
| UniProt ID | Q9Y4Z0 | [6]
| Molecular Weight | ~15 kDa | [7]
| Structure | Ring-shaped heptamer |
| Subcellular Localization | Nucleus, Cytoplasm, Stress granules |
LSM1 proteins form ring-shaped complexes:
RNA metabolism proteins represent potential targets for:
The study of Lsm1 Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
Kadie et al. LSM1 in viral replication (2018). 2018. ↩︎
Fromont-Racine et al. LSM in snRNP biogenesis (2003). 2003. ↩︎
Beggs et al. LSM family functions (2005). 2005. ↩︎