Gm Csf Receptor Alpha Chain is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| CSF2RA | |
|---|---|
| GM-CSF Receptor Alpha Chain | |
| Protein Name | GM-CSF Receptor Alpha Chain |
| Gene | CSF2RA |
| UniProt ID | P15509 |
| PDB ID | 2GYS |
| Molecular Weight | 85 kDa (predicted) |
| Subcellular Localization | Plasma membrane |
| Protein Family | Hematopoietic cytokine receptor family |
CSF2RA (GM-CSF Receptor Alpha Chain) is a protein encoded by the CSF2RA gene. It is the alpha chain of the GM-CSF receptor, which binds GM-CSF with low affinity and requires the common beta chain for signaling.
CSF2RA is a transmembrane protein with:
The GM-CSF receptor:
The study of Gm Csf Receptor Alpha Chain has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.