| CREB5 Protein — cAMP Responsive Element Binding Protein 5 | |
|---|---|
| Protein Name | cAMP-responsive element-binding protein 5 |
| Gene | [CREB5](/genes/creb5) |
| UniProt | Q8TD36 |
| Molecular Weight | 65-75 kDa (isoform-dependent) |
| Structure | bZIP transcription factor domain, transactivation domain |
| Subcellular Localization | Nucleus |
| Protein Family | CREB/ATF family |
Creb5 Protein — Camp Responsive Element Binding Protein 5 is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
CREB5 (cAMP-responsive element-binding protein 5) is a transcription factor encoded by the CREB5 gene. It belongs to the CREB/ATF family of DNA-binding proteins that regulate gene expression in response to cAMP and calcium signaling. UniProt ID: Q8TD36.
CREB5 controls expression of genes involved in:
Responds to multiple second messengers:
The study of Creb5 Protein — Camp Responsive Element Binding Protein 5 has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.