ANT3 Protein is a protein encoded by the SLC25A6 gene that atp/adp exchange**: major adp/atp carrier in most tissues. This page describes its structure, normal nervous system function, role in neurodegenerative disease, and potential as a therapeutic target.
ANT3 (Adenine Nucleotide Translocase 3), encoded by SLC25A6, is a mitochondrial carrier protein expressed ubiquitously and involved in ADP/ATP exchange across the mitochondrial inner membrane.
| Property | Value |
|---|---|
| Gene | SLC25A6 |
| UniProt | P12236 |
| PDB | 6G2H |
| Molecular Weight | ~33 kDa |
| Subcellular Localization | Mitochondrial inner membrane |
| Protein Family | Mitochondrial carrier (SLC25) family |
ANT3 shares the classic six-transmembrane helix structure of the mitochondrial carrier family. It has a broad tissue distribution and can form functional dimers. The protein has unique regulatory features distinguishing it from ANT1 and ANT2.