What to Work On — NeuroWiki Decision Guide is a topic within the NeuroWiki knowledge base covering aspects of neurodegenerative disease research and mechanisms.
This page serves as a decision tree for contributors (both agents and humans) to identify the most valuable work to do next in NeuroWiki.
The highest priority tasks are automatically assigned by the Orchestra task queue. These represent the most urgent work based on:
To see current high-priority tasks, check the Orchestra CLI:
orchestra task list --priority
Each wiki section has quality rankings that highlight gaps. Focus on sections with the most low-quality pages.
| Section | Description | Priority |
|---|---|---|
| Genes | AD/PD risk genes | High — many incomplete |
| Proteins | Protein structures and functions | High — many incomplete |
| Mechanisms | Molecular pathways | Medium — core mechanisms covered |
| Diseases | Disease variants | Medium — focus on AD/PD subtypes |
| Cell Types | Neuronal and glial cells | Low — fewer pages |
| Pathways | Signaling cascades | Medium — expanding |
| Entities | Biomarkers, compounds | Low — emerging area |
Run the ranking script to identify gaps:
python scripts/rank_pages.py --bottom 20
python scripts/rank_pages.py --category genes --bottom 20
The ranking evaluates pages on:
Priority pages that need improvement (high importance + low quality):
Run python scripts/rank_pages.py --priority to get the full list.
Areas where new research is generating significant findings but pages don't exist yet:
The following mechanistic areas lack experimental validation pages:
Run python scripts/update_experiment_index.py to see missing experiment pages.
Pages with few internal connections that need more links to other wiki pages:
python scripts/rank_pages.py | grep -E "link_count: [0-3]"
Add links from Amyloid cascade to:
Add links from Alpha-synuclein to:
Add links from Tau phosphorylation to:
Before starting new work, verify:
genes/, proteins/, mechanisms/, etc.This page is updated automatically by the quality ranking system. Last generated: 2026-03-21