TRIM11 is a brain-expressed E3 ubiquitin ligase that regulates protein quality control and has been implicated in neurodegenerative diseases. It can degrade misfolded proteins and has been studied in the context of Alzheimer's disease.
| Property | Value |
|---|---|
| Gene Symbol | TRIM11 |
| Gene Name | Tripartite Motif Containing 11 |
| Chromosomal Location | 1q42.13 |
| NCBI Gene ID | 81556 |
| OMIM | 607570 |
| UniProt | Q9C0B1 |
TRIM11 is a brain-expressed E3 ubiquitin ligase that regulates protein quality control and has been implicated in neurodegenerative diseases. It can degrade misfolded proteins and has been studied in the context of Alzheimer's disease.
The TRIM11 gene is associated with the following neurodegenerative and related diseases:
TRIM11 expression and its relevance to brain function is under active investigation.