| PCDH15 — Protocadherin 15 | |
|---|---|
| Symbol | PCDH15 |
| Full Name | Protocadherin 15 |
| Chromosome | 10q21.1 |
| NCBI Gene | 65217 |
| Ensembl | ENSG00000150275 |
| OMIM | 605653 |
| UniProt | Q9P1E5 |
| Diseases | Usher Syndrome, Hearing Loss |
| Expression | Inner ear, Cortex |
| Key Mutations | |
| Missense mutations | |
Pcdh15 — Protocadherin 15 is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
PCDH15 (Protocadherin 15) is a gene located on chromosome 10q21.1 that plays a critical role in neurodegenerative disease. Mutations in PCDH15 are associated with Usher Syndrome, Hearing Loss. The gene is catalogued as NCBI Gene ID 65217 and OMIM 605653.
The PCDH15 gene encodes a protein that is expressed in multiple brain regions including Inner ear, Cortex. The normal function of this gene product is essential for neuronal health and survival.
Expression data is available from the Allen Human Brain Atlas.
PCDH15 mutations are linked to the following neurodegenerative conditions:
Publication list pending enrichment from PubMed.
The study of Pcdh15 — Protocadherin 15 has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
Page auto-generated from NeuroWiki gene database. Last updated: 2026-02-26.