| MBD1 | |
|---|---|
| Full Name | Methyl-CpG Binding Domain Protein 1 |
| Category | Gene |
| Path | /genes/mbd1 |
MBD1 (Methyl-CpG Binding Domain Protein 1) is a gene encoding a protein that binds to methylated DNA and is involved in transcriptional repression. It plays important roles in epigenetic regulation and has been implicated in neuronal function and neurodegeneration.
MBD1 is a member of the methyl-CpG binding domain (MBD) family of proteins. It recognizes and binds to methylated CpG dinucleotides in DNA, recruiting chromatin remodeling complexes to silence gene expression. In neurons, MBD1 is involved in:
MBD1 has been linked to:
MBD1 is expressed in various brain regions including the hippocampus, cortex, and cerebellum. It shows nuclear localization in neurons.