Ntn2 Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| NTN2 Gene | |
|---|---|
| Netrin 2 | |
| Gene Symbol | NTN2 |
| Full Name | Netrin 2 |
| Chromosomal Location | 19p13.3 |
| NCBI Gene ID | 4917 |
| OMIM | 601901 |
| Ensembl ID | ENSG00000121542 |
| UniProt ID | Q8WWS8 |
Netrin-2 (encoded by the NTN2 gene) is a secreted laminin-related protein that plays crucial roles in axon guidance during neural development. It belongs to the netrin family of axon guidance molecules, which are essential for the proper wiring of the nervous system.
Netrin-2 is a secreted axon guidance molecule that:
Netrin-2 expression:
Potential roles in Alzheimer's disease:
In ALS:
Netrin-2 is used in research for:
The study of Ntn2 Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.