Lissencephaly plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Lissencephaly is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes. [1]
Lissencephaly (from Greek "lissos" meaning smooth and "enkephalos" meaning brain) is a rare brain malformation characterized by the absence of convolutions (gyri) and sulci on the surface of the brain, resulting in a smooth appearance. [2]
Lissencephaly plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications. [3]
The study of Lissencephaly has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development. [4]
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions. [^6]
Additional evidence sources: [^7]
This section highlights recent publications relevant to this disease.
Neonatal-onset epileptic encephalopathy with lissencephaly associated with a SCN3A variant: The first case in Korea and literature review. ↩︎
Expanding genetic and clinical spectra of β-tubulinopathies: A Korean study. ↩︎
MRI-based spectral analysis of fetal brain gyrification in typical development and in lissencephaly and polymicrogyria. ↩︎
Roles of microtubules and LIS1 in dynein transport machinery assembly. ↩︎