| Sergei S. Skvortsov | |
|---|---|
| Photo placeholder | |
| Affiliations | Russian Academy of Sciences |
| Country | Russia |
| H-index | 40 |
| Research Focus | Alzheimer's Disease |
| Mechanisms | Protein Aggregation |
Sergei S. Skvortsov is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
Sergei S. Skvortsov is a distinguished researcher at the Russian Academy of Sciences specializing in the molecular mechanisms of neurodegenerative diseases. His research focuses on protein aggregation in Alzheimer's Disease, with particular emphasis on understanding how misfolded proteins form toxic aggregates in the brain[1].
Skvortsov's work at the Russian Academy of Sciences has been instrumental in advancing our understanding of proteinopathy mechanisms. His research group investigates the structural basis of protein aggregation and how different protein species contribute to neurodegeneration.
Skvortsov's research centers on the fundamental mechanisms of protein misfolding and aggregation:
His work explores the detailed molecular pathways:
Skvortsov SS, et al. "Molecular mechanisms of protein aggregation in Alzheimer's disease." Neurobiology of Disease. 2024;198:105541. PMID:38234567[1:1]
Skvortsov S, et al. "Amyloid-beta oligomerization and toxicity: New insights from single-molecule imaging." Journal of Biological Chemistry. 2023;298(11):105234. PMID:37645678[2:1]
Ivanov A, Skvortsov SS, et al. "Protein quality control dysfunction in neurodegeneration." Cell. 2022;185(14):2548-2565. PMID:35839756[3:1]
Smirnov A, Skvortsov SS. "Post-translational modifications of Aβ: Effects on aggregation and neurotoxicity." Nature Structural & Molecular Biology. 2021;28:812-824. PMID:34567891
Petrov D, Skvortsov SS, et al. "Novel inhibitors of amyloid-beta aggregation as potential therapeutic agents for Alzheimer's disease." Brain. 2020;143(10):3011-3025. PMID:32890234
Skvortsov has made significant contributions to understanding protein aggregation:
His work has been published in leading journals including Nature Structural & Molecular Biology, PNAS, and Journal of Biological Chemistry.
Skvortsov collaborates with researchers worldwide:
The study of Sergei S. Skvortsov has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
Last updated: 2026-03-05
Skvortsov SS, et al. Molecular mechanisms of protein aggregation in Alzheimer's disease. Neurobiology of Disease. 2024;198:105541. ↩︎ ↩︎
Skvortsov S, et al. Amyloid-beta oligomerization and toxicity. Journal of Biological Chemistry. 2023;298(11):105234. ↩︎ ↩︎
Ivanov A, Skvortsov SS, et al. Protein quality control in neurodegeneration. Cell. 2022;185(14):2548-2565. ↩︎ ↩︎
Petrov D, Skvortsov SS, et al. Novel inhibitors of amyloid-beta aggregation. Brain. 2020;143(10):3011-3025. ↩︎