Dr. Leverenz continues to lead cutting-edge research on Lewy body disorders and atypical parkinsonism. Recent publications include:
- ATN cerebrospinal fluid biomarkers in dementia with Lewy bodies: Initial results from the United States Dementia with Lewy Bodies Consortium. Alzheimer's & Dementia. 2024.
- Concerns with the new biological research criteria for synucleinopathy. Lancet Neurology. 2024.
- Relationships between plasma biomarkers, tau PET, FDG PET, and volumetric MRI in mild to moderate Alzheimer's disease patients. Alzheimer's & Dementia: Diagnosis, Assessment and Disease Monitoring. 2024.
- X-chromosome-wide association study for Alzheimer's disease. Molecular Psychiatry. 2025.
Dr. James B. Leverenz is a neurologist specializing in neurodegenerative disorders, with particular expertise in dementia with Lewy bodies (DLB), progressive supranuclear palsy (PSP), and Alzheimer's disease. He practices at the Cleveland Clinic.
- Position: Director, Center for Neurological Restoration
- Institution: Cleveland Clinic
- Location: Cleveland, Ohio, USA
¶ Clinical and Research Focus
Dr. Leverenz's clinical and research work focuses on:
- Dementia with Lewy bodies: Diagnosis, biomarkers, and treatment
- Atypical Parkinsonism: PSP and related disorders
- Alzheimer's Disease: Clinical trials and biomarker research
- Neuroimaging: PET and MRI biomarkers for neurodegenerative diseases
Dr. Leverenz provides specialized care for patients with:
- Dementia with Lewy Bodies (DLB)
- Progressive Supranuclear Palsy (PSP)
- Alzheimer's Disease
- Other dementias and movement disorders
- Leverenz JB, et al. DLB consensus criteria: clinical correlates. Neurology. 2023.
- Leverenz JB, et al. Neuroimaging biomarkers in DLB and PSP. Movement Disorders. 2022.
- Leverenz JB, et al. Autopsy correlates of Lewy body disease. Acta Neuropathologica. 2021.
- Lewy Body Dementia Research Center: Cleveland Clinic's DLB research program focusing on biomarkers and clinical trials
- Atypical Parkinsonism Registry: Longitudinal study of PSP, CBD, and MSA patients
- Neuroimaging Core: PET and MRI imaging for neurodegenerative disease research
¶ Awards and Recognition
- Cleveland Clinic Distinguished Physician Award
- American Academy of Neurology Fellow
- Movement Disorders Society Member