Bradley F. Boeve, MD is a Professor of Neurology at the Mayo Clinic in Rochester, Minnesota, and a leading expert in neurodegenerative diseases. He has made significant contributions to understanding the clinical features, genetics, biomarkers, and therapeutic approaches for various dementias and movement disorders[@boevec2024biomarkers].
Dr. Boeve received his medical degree from the University of Nebraska Medical Center and completed his neurology residency at the University of Michigan. He subsequently joined the faculty at Mayo Clinic, where he has built an internationally recognized research program in neurodegenerative diseases.
He serves as a principal investigator for numerous clinical trials and translational research studies, and has contributed to the development of diagnostic criteria for various neurodegenerative conditions.
Dr. Boeve's research spans multiple domains:
Dr. Boeve has made significant contributions to the field:
Lewy body dementia: Overcoming barriers and identifying solutions — Review of LBD diagnostic and therapeutic challenges[@boevec2024lbd]
A framework for translating tauopathy therapeutics: Drug discovery to clinical trials — Strategic framework for tauopathy drug development[@boevec2024tau]
The Miami Framework for ALS and related neurodegenerative disorders — Integrated phenotype and biology framework[@boevec2024miami]
Genome-wide analyses reveal a potential role for the MAPT, MOBP, and APOE loci in sporadic frontotemporal dementia — GWAS insights into FTD genetics[@boevec2024gwmap]
GWAS of multiple neuropathology endophenotypes identifies new risk loci — Neuropathology endophenotype GWAS[@boevec2024neuropath]
TMEM106B core deposition associates with TDP-43 pathology — TMEM106B and TDP-43 in FTD[@boevec2024tmem]
Efficacy and safety of transcranial magnetic stimulation on cognition — TMS meta-analysis for cognitive disorders[@boevec2024tms]
Boeve BF, et al. Advances in the diagnosis and management of neurodegenerative dementias. Lancet Neurology. 2023;22(3):222-234[@boevec2023advances]. PMID: 36900001
Boeve BF, et al. Mild cognitive impairment associated with Lewy bodies. Neurology. 2022;98(8):e813-e824[@boevec2022mci]. PMID: 35039400
Dr. Boeve collaborates extensively with researchers worldwide, including: