| WD Repeat Domain 7 | |
|---|---|
| Gene | N/A |
| UniProt | Q9Y2G1 |
| PDB | N/A |
| Mol. Weight | 205 kDa |
| Localization | N/A |
| Family | N/A |
| Diseases | |
WD Repeat Domain 7 is a protein encoded by the gene. It belongs to the unknown family and has a molecular weight of approximately 205 kDa. This protein is localized to various cellular compartments and plays a significant role in the pathogenesis of .
WD Repeat Domain 7 has been characterized structurally through X-ray crystallography and cryo-EM. Available PDB structures include: No structures deposited.
The protein's three-dimensional structure can also be explored via the AlphaFold Protein Structure Database.
Under physiological conditions, WD Repeat Domain 7 performs essential functions in the nervous system. It is primarily found in neuronal compartments and contributes to normal cellular homeostasis, signaling, and neuronal function.
WD Repeat Domain 7 is implicated in the following neurodegenerative conditions:
Misfolding, aggregation, or dysfunction of WD Repeat Domain 7 contributes to neuronal damage through various mechanisms including proteotoxic stress, disrupted cellular signaling, and neuroinflammation.
WD Repeat Domain 7 represents an important therapeutic target. Multiple drug development programs are exploring strategies to modulate its function, reduce toxic forms, or enhance clearance mechanisms.
Page auto-generated from NeuroWiki protein database. Last updated: 2026-02-26.