Tfrc Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Tfrc Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| Transferrin Receptor 1 | |
|---|---|
| Protein Name | Transferrin Receptor 1 |
| Gene | TFRC |
| UniProt ID | P02786 |
| PDB ID | 1CX8 |
| Molecular Weight | 190 kDa |
| Subcellular Location | Plasma membrane |
| Protein Family | MHC class I family |
Transferrin Receptor 1 is a MHC class I family protein with characteristic structural features for metal ion transport.
TFRC is a cell surface receptor that mediates cellular iron uptake through transferrin endocytosis. It is essential for iron delivery to proliferating cells and neurons.
Iron Deficiency Anemia - Altered TFR expression affects iron homeostasis. Upregulated in AD brains.
Tfrc Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Tfrc Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.