Taci Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Taci Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| TACI Protein | |
|---|---|
| Protein Name | Transmembrane Activator and Calcium Modulator |
| Gene | TNFRSF13B (TACI) |
| UniProt ID | O14836 |
| PDB Structures | 1XU1, 1XU2 |
| Molecular Weight | 32.5 kDa |
| Subcellular Localization | Cell surface |
| Protein Family | TNF Receptor Superfamily |
TACI is a type I transmembrane receptor with two cysteine-rich domains (CRDs) in the extracellular region. It contains a transmembrane domain and a cytoplasmic tail with signaling motifs.
TACI binds BAFF and APRIL cytokines to:
Taci Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Taci Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.