| Synapsin1 Protein | |
|---|---|
| Gene | [SYN1](/genes/syn1) |
| UniProt | P17600 |
| Molecular Weight | 70 kDa |
| Subcellular Localization | Synaptic vesicles, presynaptic terminal |
| Protein Family | Synapsin family |
| PDB Structures | 1R46, 2QK7 |
Synapsin1 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
Synapsin1 is a neuronal phosphoprotein associated with synaptic vesicles that plays essential roles in synaptogenesis, synaptic plasticity, and neurotransmitter release. It is a key marker of presynaptic terminals and has been implicated in neurodegenerative diseases where synaptic loss is a hallmark feature.
Synapsin1 (706 amino acids) contains:
The study of Synapsin1 Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.