P21 Activated Kinase 3 is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| Protein Name | p21-Activated Kinase 3 |
| Gene | PAK3 |
| UniProt | O75914 |
| PDB ID | 2J0I |
| Molecular Weight | 62 kDa |
| Subcellular Localization | Postsynaptic densities, dendritic spines |
| Protein Family | PAK kinase family |
The PAK3 gene encodes the p21-Activated Kinase 3, which is involved in neuronal function and has been implicated in neurodegenerative and neurodevelopmental disorders.
p21-Activated Kinase 3 is a PAK kinase family protein with a molecular weight of approximately 62 kDa. The protein localizes to Postsynaptic densities, dendritic spines.
This protein plays important roles in the nervous system. It is involved in:
Dysfunction of this protein has been associated with various neurological disorders. Further research is ongoing to understand the precise molecular mechanisms.
Research is ongoing to develop therapeutic strategies targeting this protein for neurological disorders.
This page was created as part of the NeuroWiki protein page creation effort.
The study of P21 Activated Kinase 3 has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.