Ndufs2 Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Ndufs2 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
NDUFS2 Protein
| Protein Name | NDUFS2 Protein |
| Gene | NDUFS2 |
| UniProt ID | O75306 |
| PDB IDs | 6RCQ, 6G72 |
| Molecular Weight | 49 kDa |
| Subcellular Localization | Mitochondrial Inner Membrane |
| Protein Family | NADH Dehydrogenase Complex I Subunits |
NDUFS2 protein belongs to the NADH Dehydrogenase Complex I Subunits. The protein localizes to Mitochondrial Inner Membrane.
NDUFS2 is a core subunit of mitochondrial Complex I that participates in electron transfer and proton pumping across the inner mitochondrial membrane.
NDUFS2 mutations cause mitochondrial Complex I deficiency associated with cardiomyopathy and neurodegeneration. Complex I dysfunction is implicated in Parkinson's disease.
Investigational treatments focus on CoQ10 supplementation and gene therapy approaches.
Ndufs2 Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Ndufs2 Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.