Myt1L Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
MYT1L (Myelin Transcription Factor 1-like) is a zinc finger transcription factor crucial for neuronal differentiation and development. MYT1L is a key driver of neuronal fate commitment and is used in direct neuronal reprogramming approaches due to its powerful ability to convert non-neuronal cells into neurons. [1]
| Attribute | Value | [2]
|-----------|-------| [3]
| Protein Name | Myelin Transcription Factor 1-like | [4]
| Gene | MYT1L | [5]
| UniProt ID | Q9UL36 | [6]
| Molecular Weight | ~120 kDa | [7]
| Structure | Multiple C2H2 zinc finger domains |
| Subcellular Localization | Nucleus |
MYT1L contains:
MYT1L is being explored for:
The study of Myt1L Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
Chen et al. MYT1L and neurodevelopment (2016). 2016. ↩︎
Matsushita et al. MYT1 family in CNS (2004). 2004. ↩︎
Thom et al. MYT1L mutations in disease (2014). 2014. ↩︎