Il 18Bp Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
IL-18BP (Interleukin-18 Binding Protein) is a naturally occurring soluble protein that binds and neutralizes IL-18, a pro-inflammatory cytokine involved in the innate immune response. IL-18BP functions as a decoy receptor, preventing IL-18 from binding to its signaling receptor IL-18Rα. It has emerged as an important regulator of inflammation in neurodegenerative diseases.
| Property | Value |
|---|---|
| Protein Name | IL-18BP (Interleukin-18 Binding Protein) |
| Gene Symbol | IL18BP |
| Chromosomal Location | 11q13.4 |
| UniProt ID | O95758 |
| Molecular Weight | ~40 kDa (unglycosylated: 20 kDa) |
| Protein Length | 194 amino acids |
| Subcellular Localization | Secreted |
IL-18BP is being studied for its anti-inflammatory properties and therapeutic potential.
IL-18BP represents a promising anti-inflammatory therapeutic target. Recombinant IL-18BP is being developed as an anti-inflammatory therapy. IL-18BP studies are advancing understanding of anti-inflammatory therapies.
The study of Il 18Bp Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
[1] Research on this topic.
Current research focuses on: