Gaba A Receptor Epsilon Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
GABRE encodes the epsilon subunit of GABA-A receptors. The epsilon subunit confers unique pharmacological properties and is expressed in specific brain regions including cortex and hippocampus.
GABA-A Receptor Epsilon Protein is encoded by the GABRE gene. It is a GABA-A receptor epsilon subunit. The UniProt ID is P18507.
- Molecular Weight: 56 kDa
- Localization: Plasma membrane, Synaptic
- PDB Structures: 6HUP
GABRE encodes the epsilon subunit of GABA-A receptors. The epsilon subunit confers unique pharmacological properties and is expressed in specific brain regions including cortex and hippocampus.
The protein is expressed in Plasma membrane, Synaptic and plays important roles in cellular physiology.
GABRE mutations are implicated in epilepsy and Angelman syndrome. The epsilon subunit may play roles in neurodevelopmental disorders.
Epsilon subunit-containing receptors have distinct benzodiazepine sensitivity.
The study of Gaba A Receptor Epsilon Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
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