Ebf3 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
EBF3 (Early B-cell Factor 3) is a transcription factor critical for neuronal development and function. As a member of the Collier/Olfactory/EBF (COE) family, EBF3 is essential for proper brain development, synapse formation, and cognitive function. [1]
| Attribute | Value | [2]
|-----------|-------| [3]
| Protein Name | Early B-cell Factor 3 | [4]
| Gene | EBF3 | [5]
| UniProt ID | Q5VTU4 | [6]
| Molecular Weight | ~65 kDa | [7]
| Structure | COE family: DNA-binding domain + effector domain |
| Subcellular Localization | Nucleus |
EBF3 contains:
EBF3 is a potential target for:
The study of Ebf3 Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
NCBI Gene: EBF3. 1979. ↩︎
Wang et al. EBF3 in neuronal differentiation (2004). 2004. ↩︎
Pozniak et al. EBF3 in brain development (2010). 2010. ↩︎
Hagan et al. EBF family in CNS (2020). 2020. ↩︎