Dishevelled 1 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
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title: Dishevelled 1 Protein [2]
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| Protein Name | Dishevelled 1 | [6]
| Gene | DVL1 |
| UniProt ID | Q92997 |
| PDB ID | 1L6O, 2KDQ, 3C5G, 4WJI, 4WJJ, 4WJK |
| Molecular Weight | 70-80 kDa (alternatively spliced) |
| Subcellular Localization | Cytoplasm, Cell membrane, Synapses |
| Protein Family | Dishevelled family |
Dishevelled 1 (DVL1) is a key scaffolding protein in the Wnt signaling pathway. It is a cytoplasmic protein that transduces Wnt signals from Frizzled receptors to downstream effectors, playing essential roles in development and neuronal function.
Alzheimer's Disease:
Parkinson's Disease:
Neurodevelopmental Disorders:
The study of Dishevelled 1 Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.