Chst14 Protein Dermatan 4 O Sulfotransferase 1 is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| Dermatan 4-O-Sulfotransferase 1 | |
|---|---|
| Protein Name | Dermatan 4-O-Sulfotransferase 1 |
| Gene | CHST14 |
| UniProt ID | Q8IWW4 |
| PDB ID | N/A |
| Molecular Weight | 44 kDa |
| Localization | Golgi apparatus |
| Protein Family | Carbohydrate sulfotransferase |
This page provides comprehensive information about the subject's role in neurodegenerative diseases. The subject participates in various molecular pathways and cellular processes relevant to Alzheimer's disease, Parkinson's disease, and related conditions.
CHST14 is a Golgi-resident enzyme:
CHST14 sulfates dermatan/chondroitin:
CHST14 mutations - defective glycosaminoglycan sulfation, connective tissue disorders
No current therapy; gene therapy potential
The study of Chst14 Protein Dermatan 4 O Sulfotransferase 1 has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.