| TEAD1 — TEA Domain Transcription Factor 1 | |
|---|---|
| Symbol | TEAD1 |
| Full Name | TEA Domain Transcription Factor 1 |
| Chromosome | 11p15.4 |
| NCBI Gene | 7003 |
| Ensembl | ENSG00000187091 |
| OMIM | 189892 |
| UniProt | P28347 |
| Diseases | Alzheimer's Disease, Svevo syndrome,Vertebral fusion |
| Expression | Cerebral cortex, Heart, Muscle |
Tead1 — Tea Domain Transcription Factor 1 is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
TEAD1 (TEA Domain Transcription Factor 1) encodes a transcription factor that is a key effector of the Hippo signaling pathway. TEAD1 binds to DNA through its TEA domain and interacts with transcriptional co-activators like YAP and TAZ to regulate gene expression.
TEAD1 functions as a DNA-binding transcription factor:
TEAD1 is involved in neuronal survival:
The study of Tead1 — Tea Domain Transcription Factor 1 has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.