Snx2 is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| Sorting Nexin 2 | |
|---|---|
| Gene Symbol | SNX2 |
| Full Name | sorting nexin 2 |
| Chromosome | 5q23.1 |
| NCBI Gene ID | 6644 |
| OMIM | 605929 |
| Ensembl ID | ENSG000002聚36053 |
| UniProt ID | O60613 |
| Associated Diseases | Alzheimer's Disease, Parkinson's Disease |
This page provides comprehensive information about the subject's role in neurodegenerative diseases. The subject participates in various molecular pathways and cellular processes relevant to Alzheimer's disease, Parkinson's disease, and related conditions.
SNX2 (Sorting Nexin 2) is a close paralog of SNX1 and functions similarly in membrane trafficking:
Ubiquitously expressed with high levels in:
SNX2 collaborates with SNX1 in maintaining proper endosomal sorting, critical for neuronal protein homeostasis.
The study of Snx2 has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.