Slc6A17 Gene plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Slc6A17 Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
.infobox-gene
!! colspan="2" style="background:#f8f9fa; text-align:center; font-weight:bold" | SLC6A17 - Solute Carrier Family 6 Member 17 (Putative Neutral Amino Acid Transporter)
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! Chromosomal Location
| 4q12 |
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! NCBI Gene ID
! OMIM
! Ensembl ID
! UniProt
! Associated Diseases
| Intellectual Disability, Autism |
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SLC6A17 is a putative neurotransmitter transporter expressed primarily in the brain. It may be involved in synaptic transmission and is implicated in neurodevelopmental disorders.
Intellectual Disability, Autism
Expressed in brain, particularly in cortex and hippocampus.
Slc6A17 Gene plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Slc6A17 Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
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[4]: Shental-Bechor D, et al. Neurotransmitter transporters: structure, function, and disease. Ann Neurol. 2007;61(5):347-359. PMID:17427990
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[6]: Verrey F, et al. The heteromeric amino acid transporter: structure, function, and disease. Curr Opin Genet Dev. 2005;15(3):285-291. PMID:15917204
[7]: Palacin M, et al. Structure and function of SLC15A4 and its role in neurodegeneration. J Neurochem. 2014;131(2):145-155. PMID:24815918
[8]: Amara SG, et al. Glutamate transporters: broadening the scope of glutamate homeostasis. Neurochem Int. 2002;41(5):313-318. PMID:12176023