Slc6A14 Gene plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Slc6A14 Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
.infobox-gene
!! colspan="2" style="background:#f8f9fa; text-align:center; font-weight:bold" | SLC6A14 - Solute Carrier Family 6 Member 14 (Amino Acid Transporter)
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! Chromosomal Location
| 9q32 |
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! NCBI Gene ID
! OMIM
! Ensembl ID
! UniProt
! Associated Diseases
| Obesity, Cancer |
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SLC6A14 encodes an amino acid transporter that is overexpressed in certain cancers and may play a role in cell growth.
Obesity, Cancer
Expressed in lung, mammary gland, and brain.
Slc6A14 Gene plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Slc6A14 Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
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[2]: Kandasamy P, et al. SLC transporters as therapeutic targets. Pharmacol Rev. 2020;72(3):466-485. PMID:32295719
[3]: Hediger MA, et al. The ABCs of solute carriers: physiological, pathological and therapeutic implications. Pflugers Arch. 2004;447(5):465-468. PMID:14624363
[4]: Shental-Bechor D, et al. Neurotransmitter transporters: structure, function, and disease. Ann Neurol. 2007;61(5):347-359. PMID:17427990
[5]: Goncalves P, et al. Glucose transporters in the mammalian blood-brain barrier. J Cereb Blood Flow Metab. 2013;33(10):1562-1573. PMID:23945237
[6]: Verrey F, et al. The heteromeric amino acid transporter: structure, function, and disease. Curr Opin Genet Dev. 2005;15(3):285-291. PMID:15917204
[7]: Palacin M, et al. Structure and function of SLC15A4 and its role in neurodegeneration. J Neurochem. 2014;131(2):145-155. PMID:24815918
[8]: Amara SG, et al. Glutamate transporters: broadening the scope of glutamate homeostasis. Neurochem Int. 2002;41(5):313-318. PMID:12176023