Slc6A11 Gene plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Slc6A11 Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
.infobox-gene
!! colspan="2" style="background:#f8f9fa; text-align:center; font-weight:bold" | SLC6A11 - Solute Carrier Family 6 Member 11 (GABA Transporter 3)
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! Chromosomal Location
| 3p25.3 |
|---|
! NCBI Gene ID
! OMIM
! Ensembl ID
! UniProt
! Associated Diseases
| Epilepsy |
|---|
SLC6A11 encodes GAT3, a GABA transporter primarily expressed in astrocytes. It is important for GABA clearance from the synaptic cleft and maintaining GABAergic inhibition.
Epilepsy
Expressed in astrocytes throughout the brain.
Slc6A11 Gene plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Slc6A11 Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
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[8]: Amara SG, et al. Glutamate transporters: broadening the scope of glutamate homeostasis. Neurochem Int. 2002;41(5):313-318. PMID:12176023