SEPTIN5 is a neuronal septin enriched in presynaptic terminals. It interacts with synaptic vesicles and is involved in exocytosis. Septin5 has been implicated in Parkinson's disease and is found in Lewy bodies.
| Property | Value |
|---|---|
| Gene Symbol | SEPTIN5 |
| Gene Name | Septin 5 |
| Chromosomal Location | 22q13.31 |
| NCBI Gene ID | 5413 |
| OMIM | 602681 |
| UniProt | Q9NSD4 |
SEPTIN5 is a neuronal septin enriched in presynaptic terminals. It interacts with synaptic vesicles and is involved in exocytosis. Septin5 has been implicated in Parkinson's disease and is found in Lewy bodies.
The SEPTIN5 gene is associated with the following neurodegenerative and related diseases:
SEPTIN5 expression and its relevance to brain function is under active investigation.