SEPTIN2 is a member of the septin family of GTP-binding proteins that form filamentous structures. Septins function as scaffolds for protein complexes and are involved in cytokinesis, membrane dynamics, and neuronal function. They are implicated in neurodegenerative diseases through their role in protein aggregation and autophagy.
| Property | Value |
|---|---|
| Gene Symbol | SEPTIN2 |
| Gene Name | Septin 2 |
| Chromosomal Location | 2q37.3 |
| NCBI Gene ID | 4735 |
| OMIM | 601680 |
| UniProt | Q15020 |
SEPTIN2 is a member of the septin family of GTP-binding proteins that form filamentous structures. Septins function as scaffolds for protein complexes and are involved in cytokinesis, membrane dynamics, and neuronal function. They are implicated in neurodegenerative diseases through their role in protein aggregation and autophagy.
The SEPTIN2 gene is associated with the following neurodegenerative and related diseases:
SEPTIN2 expression and its relevance to brain function is under active investigation.