Ppp5C is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| Protein Phosphatase 5 Catalytic Subunit | |
|---|---|
| Gene Symbol | PPP5C |
| Full Name | Protein phosphatase 5 catalytic subunit |
| Chromosome | 19p13.3 |
| NCBI Gene ID | 5536 |
| OMIM | 176843 |
| Ensembl ID | ENSG00000111454 |
| UniProt ID | P62937 |
| Associated Diseases | Alzheimer's Disease, Parkinson's Disease, Cancer |
PPP5C encodes protein phosphatase 5 (PP5), a serine/threonine phosphatase that regulates:
Widely expressed in all tissues including brain. PP5 is particularly important in neuronal signaling pathways.
| Disease | Mechanism |
|---|---|
| Alzheimer's Disease | Tau dephosphorylation |
| Parkinson's Disease | Dopamine signaling |
The study of Ppp5C has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
This section provides background information on the gene/protein and its role in the nervous system.
This overview section needs to be expanded with relevant scientific information from peer-reviewed sources.