Nqo2 Gene plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Nqo2 Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes. [1]
NQO2 (NAD(P)H Quinone Dehydrogenase 2) is a detoxification enzyme that plays important roles in cellular protection against oxidative stress. It has been implicated in Parkinson's disease and represents a potential therapeutic target. [2]
| Property | Value |
|---|---|
| Gene Symbol | NQO2 |
| Full Name | NAD(P)H Quinone Dehydrogenase 2 |
| Chromosomal Location | 5q33.2 |
| NCBI Gene ID | 4835 |
| OMIM ID | 160425 |
| Ensembl ID | ENSG00000124368 |
| UniProt ID | P16083 |
NQO2 is a ~25 kDa flavoprotein:
NQO2 performs essential protective functions:
| Brain Region | Expression Level |
|---|---|
| Substantia Nigra | High |
| Hippocampus | Moderate-High |
| Cerebral Cortex | Moderate |
| Cerebellum | Moderate |
| Striatum | High |
NQO2 is expressed in:
Nqo2 Gene plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Nqo2 Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.