Ms4A2 Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| MS4A2 | |
|---|---|
| Gene Symbol | MS4A2 |
| Full Name | Membrane Spanning 4-Domains A2 (FcεRIβ) |
| Chromosomal Location | 11q12.2 |
| NCBI Gene ID | 2538 |
| OMIM ID | 147138 |
| Ensembl ID | ENSG00000149507 |
| UniProt ID | Q08431 |
| Encoded Protein | FcεRIβ |
| Associated Diseases | Alzheimer's Disease, Atopic Dermatitis |
MS4A2 encodes the beta subunit of the high-affinity IgE receptor (FcεRI). It plays a role in mast cell and basophil activation.
Key functions:
MS4A2 is expressed in:
The study of Ms4A2 Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.