| LAMA2 — Laminin Subunit Alpha 2 | |
|---|---|
| Symbol | LAMA2 |
| Full Name | Laminin Subunit Alpha 2 |
| Chromosome | 6q22.33 |
| NCBI Gene | 3908 |
| Ensembl | ENSG00000196559 |
| OMIM | 156225 |
| UniProt | P24071 |
| Diseases | Congenital Muscular Dystrophy, Merosin-Deficient Muscular Dystrophy, Peripheral Neuropathy |
| Expression | Skeletal Muscle, Peripheral Nerve, Brain |
| Key Mutations | |
| R涯 4-8 deletion Compound heterozygosity |
|
LAMA2 (Laminin Subunit Alpha 2) is a gene located on chromosome 6q22.33 that plays a critical role in neurodegenerative disease. Mutations in LAMA2 are associated with Congenital Muscular Dystrophy, Merosin-Deficient Muscular Dystrophy, Peripheral Neuropathy. The gene is catalogued as NCBI Gene ID 3908 and OMIM 156225.
The LAMA2 gene encodes a protein that is expressed in multiple brain regions including Skeletal Muscle, Peripheral Nerve, Brain. The normal function of this gene product is essential for neuronal health and survival.
Expression data is available from the Allen Human Brain Atlas.
LAMA2 mutations are linked to the following neurodegenerative conditions:
Page auto-generated from NeuroWiki gene database. Last updated: 2026-02-26.