Kif3B — Kinesin Family Member 3B is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| KIF3B | |
|---|---|
| Full Name | Kinesin Family Member 3B |
| Chromosome | 20q11.21 |
| NCBI Gene ID | 9377 |
| Ensembl ID | ENSG00000101955 |
| OMIM ID | 604530 |
| UniProt ID | P49404 |
| Associated Diseases | Joubert Syndrome |
KIF3B (Kinesin Family Member 3B) is a gene involved in neuronal function and intracellular transport. The gene is located on chromosome 20q11.21.
KIF3B encodes a member of the kinesin family of proteins. Kinesins are motor proteins that transport cargo along microtubules, playing essential roles in intracellular organization, vesicle trafficking, and cell division.
Mutations in KIF3B are associated with several disorders:
The gene is primarily expressed in:
Further research is needed to identify key publications for this gene.
The study of Kif3B — Kinesin Family Member 3B has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.