Kif2C Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
.infobox .infobox-gene { [1]
background-color: #f8f9fa; [2]
border: 1px solid #ddd; [3]
padding: 10px; [4]
width: 300px; [5]
font-size: 0.9em; [6]
} [7]
.infobox .infobox-gene .gene-symbol {
font-weight: bold;
font-size: 1.2em;
color: #2c5282;
}
.infobox .infobox-gene .gene-name {
font-style: italic;
margin-bottom: 10px;
}
.infobox .infobox-gene table {
width: 100%;
border-collapse: collapse;
}
.infobox .infobox-gene td {
padding: 4px;
vertical-align: top;
}
.infobox .infobox-gene td.label {
font-weight: bold;
width: 40%;
color: #555;
}
.infobox .infobox-gene td.value {
width: 60%;
}
.infobox .infobox-gene a {
color: #0066cc;
text-decoration: none;
}
.infobox .infobox-gene a:hover {
text-decoration: underline;
}
| Symbol | KIF2C |
| Full Name | Kinesin Family Member 2C |
| Chromosome | 1p34.2 |
| NCBI Gene | [11004](https://www.ncbi.nlm.nih.gov/gene/11004) |
| OMIM | [616437](https://www.omim.org/entry/616437) |
| Ensembl | [ENSG00000183580](https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000183580) |
| UniProt | [Q9UBX6](https://www.uniprot.org/uniprotkb/Q9UBX6/entry) |
| Associated Diseases | Cancer (relevant to neurodegeneration research) |
KIF2C (Kinesin Family Member 2C) is a mitotic kinesin that regulates microtubule depolymerization during cell division. While primarily studied in cancer biology, KIF2C is expressed in neurons and may play roles in neuronal development and axonal transport. Dysregulated KIF2C has been implicated in neurodegenerative diseases.
KIF2C is a mitotic kinesin with microtubule-depolymerizing activity. While primarily studied in cell division, it may have roles in neuronal transport and synaptic function.
Expressed in dividing cells and neurons.
The study of Kif2C Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
Kline-Smith et al. Kinesin-13 depolymerases and neuronal microtubules (2019). 2019. ↩︎
Mennella et al. Motor proteins in neuronal transport (2015). 2015. ↩︎
Hirokawa et al. Kinesin superfamily proteins in neurons (2020). 2020. ↩︎
Baas et al. Microtubule regulation in neurons (2017). 2017. ↩︎
Guzman et al. Neuronal cytoskeleton and transport in disease (2018). 2018. ↩︎
Kapoor et al. Kinesin-13 family in neuronal development (2016). 2016. ↩︎
Stout et al. Cytoskeletal dynamics in brain disorders (2019). 2019. ↩︎