Kif21B — Kinesin Family Member 21B is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| KIF21B | |
|---|---|
| Full Name | Kinesin Family Member 21B |
| Chromosome | 1p31.3 |
| NCBI Gene ID | 22873 |
| Ensembl ID | ENSG00000145794 |
| OMIM ID | 609783 |
| UniProt ID | Q9Y4G1 |
| Associated Diseases | Neurodevelopmental disorders |
KIF21B (Kinesin Family Member 21B) is a gene involved in neuronal function and intracellular transport. The gene is located on chromosome 1p31.3.
KIF21B encodes a member of the kinesin family of proteins. Kinesins are motor proteins that transport cargo along microtubules, playing essential roles in intracellular organization, vesicle trafficking, and cell division.
Mutations in KIF21B are associated with several disorders:
The gene is primarily expressed in:
The study of Kif21B — Kinesin Family Member 21B has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.