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| Symbol | CHRNA2 |
| Full Name | Cholinergic Receptor Nicotinic Alpha Subunit 2 |
| Chromosome | 8p21 |
| NCBI Gene | 1135 |
| OMIM | 104500 |
| Ensembl | ENSG00000120288 |
| UniProt | P43681 |
| Associated Diseases | Epilepsy, autonomic dysfunction |
CHRNA2 (Cholinergic Receptor Nicotinic Alpha 2) is a nicotinic acetylcholine receptor subunit that forms ligand-gated ion channels. Nicotinic receptors are crucial for fast synaptic transmission and regulate neuronal excitability, cognitive function, and synaptic plasticity. CHRNA2 has been implicated in neurodegenerative diseases and addiction.
CHRNA2 encodes the alpha-2 subunit of nicotinic acetylcholine receptors. Forms heteromeric receptors with beta subunits.
Expressed in brain and autonomic nervous system.