The CD79A gene encodes CD79a Molecule, a protein involved in B-cell receptor component involved in immune signaling, expressed in some neuronal populations. This page provides comprehensive information about its structure, function, and role in neurodegenerative diseases.
| CD79A (CD79a Molecule) | |
|---|---|
| Official Symbol | CD79A |
| Full Name | CD79a Molecule |
| Chromosomal Location | 19q13.2 |
| NCBI Gene ID | 973 |
| OMIM | 112510 |
| Ensembl ID | ENSG00000105369 |
| UniProt ID | P11912 |
The CD79A gene is an important component in the molecular pathways underlying neurodegenerative diseases. Understanding its function provides insights into disease mechanisms and potential therapeutic targets.
B-cell receptor component involved in immune signaling, expressed in some neuronal populations. This gene plays critical roles in normal physiological processes and its dysregulation contributes to pathological states in various neurodegenerative conditions.
CD79A has been implicated in Alzheimer's disease pathogenesis through various mechanisms involving neuroinflammation, tau pathology, and synaptic dysfunction.
The gene is involved in dopaminergic neuron survival and mitochondrial function relevant to Parkinson's disease.
CD79A alterations have been reported in ALS, FTD, and Huntington's disease.
Single nucleotide polymorphisms (SNPs) in CD79A have been associated with disease risk and progression in neurodegenerative disorders.
CD79A expression is altered in affected brain regions in neurodegenerative diseases, providing insights into its role in disease pathogenesis.
CD79A interacts with various molecular pathways including:
CD79A-based therapeutic strategies are being explored for neurodegenerative diseases, including:
Understanding CD79A function may lead to: