Calca Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| Gene Symbol | CALCA |
|---|---|
| Full Name | calcitonin alpha |
| Chromosomal Location | 11p15.2 |
| NCBI Gene ID | [https://www.ncbi.nlm.nih.gov/gene/796 796] |
| OMIM | [https://www.omim.org/entry/114090 114090] |
| Ensembl ID | ENSG00000110680 |
| UniProt ID | [https://www.uniprot.org/uniprot/P01258 P01258] |
| Associated Diseases | [Migraine](/diseases/migraine), [Alzheimer's Disease](/diseases/alzheimer-disease), [Stroke](/diseases/stroke) |
This page provides comprehensive information about the subject's role in neurodegenerative diseases. The subject participates in various molecular pathways and cellular processes relevant to Alzheimer's disease, Parkinson's disease, and related conditions.
CALCA encodes both calcitonin and α-CGRP (Calcitonin Gene-Related Peptide) through alternative splicing. α-CGRP is a potent neuropeptide involved in pain transmission, neuroinflammation, and vasodilation.
CALCA is expressed in:
The study of Calca Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.