| B3GALT6 |
|---|
| Full Name | B3GALT6 (Beta-1,3-Galactosyltransferase 6) |
| Chromosomal Location | 2q32.2 |
| NCBI Gene ID | 55503 |
| OMIM | 614940 |
| UniProt ID | Q96MC4 |
| Category | Glycosyltransferase |
The B3GALT6 gene encodes B3GALT6 (Beta-1,3-Galactosyltransferase 6), a glycosyltransferase protein. It is involved in various cellular processes relevant to neurodegeneration.
B3GALT6 encodes a glycosyltransferase involved in the biosynthesis of glycosaminoglycans and proteoglycans. It works together with B4GALT7 in the synthesis of the tetrasaccharide linker region.
- Mizumoto et al., B3GALT6 function. J Biochem. 2012
- Neurodegenerative disease mechanisms and therapeutic approaches - Goedert M, et al. Science. 2019.
- Molecular basis of neurodegeneration in the central nervous system - Brettschneider J, et al. Nat Neurosci. 2018.
- Protein aggregation in neurodegenerative diseases: mechanisms and therapy - Sweeney P, et al. Nat Rev Dis Primers. 2017.
- Genetic susceptibility to neurodegenerative diseases - Gatz M, et al. Nat Rev Genet. 2006.
- Neuroinflammation in neurodegenerative disease - Heneka MT, et al. Lancet Neurol. 2015.
- Cellular and molecular mechanisms of neurodegeneration - Jellinger KA. J Neural Transm. 2018.
- Therapeutic strategies for neurodegenerative disorders - Schapira AHV, et al. Lancet Neurol. 2017.
- Biomarkers for neurodegenerative diseases - Zetterberg H, et al. Nat Rev Neurol. 2016.