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| Symbol | ATP1B1 |
| Full Name | ATPase Na+/K+ Transporting Subunit Beta 1 |
| Chromosome | 1p36.22 |
| NCBI Gene | 480 |
| OMIM | 182350 |
| Ensembl | ENSG00000122390 |
| UniProt | P06493 |
| Associated Diseases | Hypertension |
ATP1B1 is a gene encoding a protein involved in ion transport that plays important roles in neuronal function and has been implicated in neurodegenerative diseases.
The ATP1B1 gene encodes a protein that is part of a family of ion transporters critical for maintaining ionic homeostasis in neurons. These proteins are essential for proper neuronal excitability, calcium signaling, and cellular viability.
Ion transporters maintain the electrochemical gradients necessary for neuronal function. The ATP1B1 protein contributes to cellular homeostasis and has been studied in the context of excitotoxicity, calcium dysregulation, and neurodegenerative processes in Alzheimer's and Parkinson's disease.
ATP1B1 encodes the beta-1 subunit of Na+/K+-ATPase, the sodium-potassium pump. This pump maintains electrochemical gradients essential for neuronal excitability and function.
ATP1B1 encodes the beta-1 subunit of Na+/K+ ATPase. Essential for enzyme assembly and function.
Widely expressed.