Calm2 Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
.infobox .infobox-gene
| Gene Symbol | CALM2 |
|---|---|
| Gene Name | Calmodulin 2 |
| Chromosome | 2p21 |
| NCBI Gene ID | 805 |
| OMIM ID | 114182 |
| Ensembl ID | ENSG00000165458 |
| UniProt ID | P0DP24 |
| Associated Diseases | Long QT Syndrome, Cardiomyopathy, Neurodevelopmental Disorders |
| --- | --- |
| Categories | Calcium Signaling, Synaptic Plasticity |
This section provides a comprehensive overview of the gene/protein and its role in the nervous system and neurodegenerative diseases.
Calmodulin 2 is a calmodulin isoform with identical protein sequence to CALM1. It is expressed in various tissues including heart and brain. CALM2 mutations are associated with cardiac arrhythmias and neurodevelopmental disorders. Calmodulin is essential for calcium-dependent signaling in synaptic plasticity and learning.
The CALM2 gene is associated with several diseases.
The study of Calm2 Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.