Temporal lobe epilepsy (TLE) is the most common focal epilepsy in adults and is strongly associated with hippocampal, perirhinal, and broader medial temporal network dysfunction.[1][2] In NeuroWiki it mainly serves as a canonical disease target for temporal-lobe cell-type pages that discuss seizure vulnerability and circuit remodeling.
TLE is useful here as a disease-level anchor for links from temporal-lobe neuron pages and for comparisons between epileptic network remodeling and neurodegenerative circuit dysfunction.[1:1][2:1]
Genetics of temporal lobe epilepsy: a review. Journal of Biomedicine and Biotechnology (2012). ↩︎ ↩︎
Perirhinal cortex and temporal lobe epilepsy. Neuroscience (2013). ↩︎ ↩︎