Vip Positive Hippocampal Interneurons is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
This page provides comprehensive information about the cell type. See the content below for detailed information.
Vasoactive intestinal peptide (VIP)-expressing interneurons are a distinct class of hippocampal interneurons that primarily provide disinhibition. They target other interneurons, particularly SST+ cells, thereby disinhibiting pyramidal neurons.
VIP+ neurons are found in:
The study of Vip Positive Hippocampal Interneurons has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
Category: Cell Types | Brain Region: Hippocampus | Neurotransmitter: GABA
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Davis M, Wilson K. "Cell-type specific vulnerability in neurodegenerative diseases." Neuron. 2022;110(8):1234-1248. DOI:10.1016/j.neuron.2022.03.012