Resistin is an adipokine that induces insulin resistance and inflammation.
| Property |
Value |
| Category |
Metabolic Hormone Neurons |
| Location |
Hypothalamus, Macrophages |
| Hormone |
Resistin (RETN) |
| Receptors |
RETN4, TLR4 |
- Resistin: 108 amino acids (human)
- Cysteine-rich: Disulfide bonds
- Adipocyte/macrophage: Sources
- SOCS3: Cytokine signaling
- AMPK: Energy sensing
- Inflammation: Pro-inflammatory
- Hepatic: Glucose production
- Adipocyte: Lipogenesis
- Muscle: Glucose uptake
- Cytokines: Pro-inflammatory
- Macrophage: Polarization
- Atherosclerosis: Vascular effects
- Resistin: Insulin resistance
- Obesity: Resistin levels
- Therapeutic: Targeting
- Resistin: Vascular inflammation
- Cardiovascular: Risk factor
- Therapeutic: Resistin blocking
- Steppan. Resistin discovery (2001)
- Lazar. Resistin (2007)